Position Title: Scientist II
Work Location: South San Francisco, CA, 94080
Assignment Duration: 12 Months
Work Arrangement: Onsite
Position Summary:
The Protein Sciences organization within our organization Research and Early Development is seeking a highly motivated, scientifically curious, skilled, and productive research associate to advance efforts on drug discovery and gene therapy modalities in a contract role. This position offers hands-on experience in drug discovery. The candidate will be expected to work independently, to generate data and communicate results that drive project decisions.
Key Responsibilities:
* Cell culture, flow cytometry, AAV QC and transduction efficiency experiments
* Biophysical, biochemical & biological analyses such as SPR/BLI for PPI assessment, enzymatic activity assays
* Operating FPLC for protein purification
* Cloning and mutagenesis
* Independently design and execute well-controlled experiments
* Collect, analyze, interpret, and effectively communicate data
* Collaborate across research groups to support the development of therapeutics for both intracellular and extracellular targets
* Communicating with and presenting to collaborators across the research community Qualification & Experience:
* BS, MS, or PhD in molecular virology, biochemistry, protein engineering, molecular biology, or a related discipline, with significant wet-lab experience w/5 years of exp
* Knowledge of basic wet-lab skills including, but not limited to: protein purification (FPLC) and characterization, PCR, construct design, cloning, biochemical and biophysical assays
* Proficiency with mammalian cell culture, flow cytometry and experience working with adeno associated viruses (AAVs) is strongly preferred
* Excellent organizational communication and interpersonal skills required
* Motivated, collaborative, self-directed, efficient
* Meticulous, detail-oriented and organized, with excellent problem solving and analytical skills
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