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Senior Director, Translational Medicine

Exelixis
paid holidays, sick time, 401(k)
United States, California, Alameda
Sep 03, 2025

SUMMARY/JOB PURPOSE:

In collaboration with clinical and project teams, design and execute translational medicine programs for early and late-stage clinical trials. Provide scientific input and manage team responsible for data collection, analysis, and interpretation of results from biomarker studies, and effectively engage with cross-functional teams to share results both internally and externally. Collaporate with discovery research to provide feedback and translational medicine support programs for early stage programs. Providing scientific leadership is an essential part of this role.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

  • Lead the development and implementation of translational medicine programs for company sponsored clinical studies
  • Represent the translational medicine function in cross-functional development teams
  • Work cross-functionally within Exelixis, and partners with external collaborators and vendors, to execute translational medicine studies
  • Write and review translational medicine aspects of clinical documents (e.g., protocols, informed consents, etc).
  • Identify appropriate assays and vendors to perform analysis of biomarker samples
  • Ensure biomarker testing is completed on schedule, and critically analyzes and interprets results from these studies
  • Communicate biomarker results to internal teams and management
  • Engage with investigators to plan translational medicine programs and share results
  • Collaborate with discovery research to develop and execute nonclinical translational medicine programs
  • Ensure completion of translational medicine activities
  • Identify and manage studies with contract research organizations

SUPERVISORY RESPONSIBILITIES:

  • Directly supervises employees/team
  • Work with direct reports to design and implement translational medicine programs
  • Provide scientific and strategic input to direct reports
  • May indirectly supervises employee(s) through a dotted line structure

EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS:

Education/Experience:

  • Doctoral degree (Ph.D.) and a minimum of twelve years related experience; or,
  • Equivalent combination of education and experience.

Experience/The Ideal for Successful Entry into Job:

  • PhD in related discipline and a minimum of 7 years of translational medicine experience in mid or large size oncology drug discovery organizations or academia
  • Experience successfully working with cross-functional teams

Knowledge/Skills:

  • Experience in designing, implementing, and publishing both nonclinical and clinical translational medicine programs
  • Proven track record of success
  • Familiar with specimen types and relevant platform technologies used to investigate mechanisms of response and resistance to oncology therapeutics
  • Scientific and strategic leader with strong analytical and communication skills
  • Ability to identify and prioritize key deliverables for complex programs
  • Familiarity on the discovery and clinical development process

WORKING CONDITIONS:

  • Work on site in Alameda, CA a minimum of 3 days per week
  • 10-25% travel requirement

DISCLAIMER

The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state, or local protected class.

#LI-JP1

If you like wild growth and working with happy, enthusiastic over-achievers, you'll enjoy your career with us!

Our compensation reflects the cost of labor across severalU.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this positionis $241,000 - $342,500 annually. The base pay range may take into account the candidate's geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidate's geographic region, job-related knowledge, skills, experience and internal equity, among other factors. In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.

DISCLAIMER
The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

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