Staff Research Associate

M_PEDS-HEMATOLOGY

Full Time

83758BR

Job Summary

The Saba Lab at UCSF investigates the role of sphingolipids in health and disease, with particular interest in the pathophysiology and treatment of sphingosine phosphate lyase insufficiency syndrome (SPLIS). Specific goals include: (1) to determine the natural history of SPLIS; (2) generate murine models of disrupted sphingolipid metabolism; (3) generate human preclinical models of disrupted sphingolipid metabolism; (4) use mouse models to dissect the signaling pathways by which sphingolipids regulate homeostasis of organ function; (5) use human models such as neurally reprogrammed fibroblasts and induced pluripotent stem cells to reveal the role of sphingolipids in organ function; (7) use gene and cell therapies to rescue phenotypes associated with disrupted sphingolipid metabolism. This SRA 1 position is for an individual who will work on sphingolipid research in mouse models and cell lines. SRA duties will include: cell/tissue culture, biochemical assays (western blotting, immunoprecipitation, qPCR), DNA and RNA extraction and manipulation, PCR and agarose gel electrophoresis, generation of recombinant retroviruses/lentiviruses, adeno associated viruses, and transduction of fibroblasts, flow cytometry, maintenance of accurate/complete/legible records, organization and maintenance of mouse colonies (including computerized record-keeping, breeding, monitoring and genotyping), and experimental procedures using laboratory mice (blood sampling, intravenous/intraperitoneal injection, dissection, analysis of harvested tissues).

The final salary and offer components are subject to additional approvals based on UC policy.

Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.

The salary range for this position is $26.00 - $31.04 (Hourly Rate).

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

Department Description

The Department of Pediatrics is one of the largest and most complex departments in the School of Medicine. The Department is comprised of 18 divisions employing over 400 core faculty. The Department ranks 21st in the nation among pediatric departments for funding from the National Institutes of Health.

Required Qualifications

• BA/BS in a related science and knowledge of, or experience with, the basic techniques or methods required by the position; and/or an equivalent combination of education and experience

Preferred Qualifications

• Expertise in breeding and maintaining laboratory mice
• Molecular biology skills including DNA/RNA extraction and PCR amplification
• Tissue culture skills including passaging cell lines
• Biochemistry skills including Western blotting

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Organization

Campus

Job Code and Payroll Title

009613 SRA 1

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees - Research Support Professionals Unit (UPTE-RX)

Employee Class

Career

Percentage

100%

Location

Oakland, CA

Campus

Benioff Children's Hospital

Work Style

Fully On-Site

Shift

Days

Shift Length

8 Hours

Additional Shift Details

M-F 8-5